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498 Additionally, left ventricular noncompaction (LVNC) is a cardiomyopathy caused by arrested compaction, characterized by excessive trabeculation with deep intertrabecular recesses and thin compact myocardium

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Some studies in mouse hyperlipidemia models have shown that the NLRP3 inflammasome can cause AS, but it may require a second insult, such as oxidized mitochondrial DNA accumulation or impaired cholesterol efflux, which may cause serious systemic inflammatory (68)